This unique procedure uses the patient’s own blood so there is no risk or rejection or complications.  It is all natural unlike the injectable fillers that are on the market.  The procedure take only about 30 minutes in a safe and sterile environment.  Blood is drawn from the patient and then is put into a centrifuge where the growth-rich platelets are separated.  These platelets are then put into a calcium chloride solution which causes them to release growth factors.  The patient is numbed with a topical anesthetic and then the growth-factor platelets are injected into the areas needed.  There are no side effects, little or no discomfort and the patient is able to return to work.
Hyaluronic acid (HA) fillers (like Juvederm and Restylane) lift the skin away from the bone to restore youthful volume and shape. But HA fillers can cause problems near the eye. Also, the injector of HA fillers can chase a wrinkle and create a shape that looks foreign to the person's face or even foreign to this planet. The HA fillers do little to improve skin tone and texture.
PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation.[1] While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 As of March 2011 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation.[1] Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications.[1]
This procedure has garnered a lot of media attention because of its popularity with movie stars and celebrities and its sensational nickname. Patients come to the Advanced Dermatology clinic having heard about this treatment in the media. They are intrigued by its touted ability to refresh skin and erase wrinkles. They also arrive with many questions, muddled facts and misinformation they heard ‘somewhere’ or from ‘someone’.

Using numbing cream and a very small needle (for almost no pain), the patient’s own growth factors are injected back into her face in a particular way. These growth factors then activate multipotent stem cells already in the skin which is tricking them into “thinking” there’s been an injury and new younger tissue is generated. The multipotent stem cells then develop into new collagen, new blood vessels, and new fatty tissue trying to “repair” the skin that was never injured!
Platelets, Zeichner explains, are rich in growth factors, which essentially act as energy boots for our skin. This helps our skin function optimally, increasing everything from collagen to elastin, while also bringing antioxidant and hydrating properties. "Platelet-rich plasma is now commonly used topically as part of a regular facial, used along with microneedling to enhance penetration into the skin, and is even being injected into the skin in the same manner as dermal fillers," says Zeichner.
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