Executing the technical aspects of the PRP process so that you get all of the added benefits: PRP is a new technology, but to the extent that it has been studied thus far, we know that the processes used to isolate and concentrate the serum is very important in terms of its effectiveness. We use a system that creates a serum that has 8x the concentration of growth and healing factors found in normal blood. Typical systems used by other practices often get concentrations in the 2-3x range.
Because the procedure utilizes the body’s own rich blood, it revitalizes and enhances the skin in a way that synthetic products can’t without side effects or surgery.  The platelet growth factors, platelet rich fibrin matrix [PRFM], stimulate new growth and energy to correct lines, wrinkles and enhance color.  It uses your own body to help beautify your body.
The idea is that this will cause skin to appear younger — and for skin care nerds, this makes the few-hundred-dollar price tag and non-minuscule amount of pain worth it. The prevailing attitude toward skin care these days seem to be, “Even if there haven’t been loads of studies about whether or not this one product will erase all my wrinkles, it still might, and also it’s probably not going to harm me.”
"While it has become incredibly popular and can yield wonderful results, it is not necessarily the miracle treatment some advertise it as," Hah said. "That being said, PRP has been used for last two decades to help treat musculoskeletal pain and regenerate cells; it is not a new “fad” treatment. In fact, studies have shown that PRP effectively promotes tissue remodeling in aging skin."
You will be asked to drop smoking in advance of the operation. Certain medications that increase the risk of bleeding such as Aspirin, non-steroidal anti-inflammatory medications, and some vitamins/homeopathic regimens should be discontinued prior to surgery. Having long hair before the surgery is going to help you cover the incisions while they heal. Any chemical processing of your hair should be done prior to surgery.

"Maybe there's still some blood in it," suggests Sclafani, who's done extensive research on the competing $1,500 Selphyl system. He also injects platelet-rich plasma for facial rejuvenation, but without mixing in the added fillers. It's a simple injection, much like getting Botox or Restalyne. "No needle is fun, but most people are able to do this without any anesthesia," he says. "They shouldn't scream in pain like that."

A vampire facial is a combination of microneedling and PRP. Platelet Rich Plasma (PRP) is a concentrate of platelet-rich plasma protein derived from the whole blood after it has been processed by spinning in a centrifuge to remove the red cells. The PRP has a greater concentration of growth factors than the whole blood. And growth factors are what our cells make that can help tissue heal and repair, which means it can help with all sorts of skin issues.
"The term “vampire facial” may throw some people off, leading to a misconception that this is a quick, easy treatment," Hah said. "However, PRP therapy is a medical procedure that should always be performed by a physician who has specific experience with the technique. In addition to blood needing to be drawn safely and with sterile instruments, micro-injuries are created in the facial skin during the microneedling process—which can leave room for infection if the proper care is not taken."
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But, you know what wasn’t disappointing? The day-three results. While the hours immediately following the hour-long appointment were characterized by an unsightly red, ultra-puffy complexion (which was really just exacerbated by the fact that I have sensitive skin), with the help of an even layer of Alastin Regenerating Skin Nectar (the post-treatment product Dr. Peredo told me to use for the next week), by day two it looked like I had a low-key sunburn and day three my skin looked radiant and refreshed. 
Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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