One of the reasons the PRP Facial is so popular is because it works miracles on acne scars and stretch marks. It also increases skin’s elasticity, fights wrinkles by stimulating collagen, and has no side effects. How does it work? When Platelet-rich plasma is applied before and after microneedling it releases at least eight essential growth factors and signaling proteins into the skin. These work to repair tissue and blood vessels, promote the growth of new tissue, and boost healthy cell production.
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“Selphyl is not a filler – it’s a truly regenerative treatment that involves harvesting the body’s own wound healing and regenerative growth factors to improve skin texture, as well as age-related changes like fine lines and laxity,” says Dr. Jennifer Pearlman, staff physician at Mount Sinai Hospital, menopause clinic and owner of PearlMD Rejuvenation, where the treatment is also offered.

Yasemin is a staff writer at Live Science, writing about biology and neuroscience, among other science topics. Yasemin has a biomedical engineering bachelors from the University of Connecticut and a science communication graduate certificate from the University of California, Santa Cruz. When she's not writing, she's probably taking photos or sitting upside-down on her couch thinking about thinking and wondering if anyone else is thinking about thinking at the exact same time.
"It's one of the most popular treatments at my practice," says Gary Goldenberg, M.D., assistant clinical professor of dermatology at the Icahn School of Medicine at Mount Sinai Hospital. "We use it to treat acne, acne scarring, melasma, surgical scars, and fine wrinkles and lines." (PRP can also be used on your scalp to treat hair loss because it can stimulate hair growth.)
Briefly, here's how it works: A doctor will draw blood from you, spin it in a centrifuge to extract the PRP, and then inject or apply it topically. The treatment "is being used to improve skin tone and texture, smooth fine lines, and even promote hair growth," Joshua Zeichner, director of clinical and cosmetic research in dermatology at Mount Sinai Hospital in New York City previously told Allure.
We may use numbing injections to make your procedure more comfortable. Dermal fillers often include some of this medication, called lidocaine, which is very similar to what dentists use when filling cavities. So we don’t always have to add more numbing injections, but it is available if needed. The numbing sensation lasts a few hours. When it wears off you shouldn’t expect to need any pain medication.
With my face completely numb and my platelet-rich plasma ready to go, I hopped onto the table. From there Rhiannon and I discussed the microneedling I had been bracing for. She explained that she would adjust the pen to penetrate my skin anywhere from .5 mm to 2 mm deep depending on the area of my face. On parts with less fat, like my forehead and around my nose, the pen would go just .5 mm deep. On the rest of my face she would bump it up to 1 mm. Once all of those details were squared away I felt confident to start the treatment. Bring it on!
Most of the people who have opted to try a vampire facial treatment rave about the results. The procedure usually starts by applying a mild numbing agent to the face, and a simple blood draw from your arm. Much like the PRP process for internal joint and muscle injuries, for the vampire facial, your blood is placed in a centrifuge to concentrate the platelets in the blood for extraction. While your platelets are being concentrated, your specialist will perform a process called micro-needling on your face. The process involves using a tool to make tiny pricks on your skin to open access for the PRP treatment. When the platelets are ready, they are applied to the face, and the growth factors are called to the site of each skin prick to repair the location with new collagen. The result is a more youthful looking appearance, minimized pores, even tone and complexion and increased elasticity.
No, a Vampire Facial mixes PRP with Microneedling to address skin texture and thickness. It doesn’t offer the lifted result that a Vampire Facelift does, and it doesn’t address wrinkles. Typically, Vampire Facials are more of a preventative treatment used by younger patients who want to build collagen actively before it starts to diminish with age, or for those who are looking to improve mild acne scarring without the downtime of a laser.

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Platelets, Zeichner explains, are rich in growth factors, which essentially act as energy boots for our skin. This helps our skin function optimally, increasing everything from collagen to elastin, while also bringing antioxidant and hydrating properties. "Platelet-rich plasma is now commonly used topically as part of a regular facial, used along with microneedling to enhance penetration into the skin, and is even being injected into the skin in the same manner as dermal fillers," says Zeichner.
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