After an initial consultation appointment, a second visit is required for the actual procedure: Blood is drawn (just like a regular blood test) and then spun in a centrifugation system to separate the platelet-rich plasma (PRP) from the other blood elements. This is then injected with tiny needles into the superficial layers of the skin (called mesotherapy).

So, what is it and how does it work, exactly? Don't let the name fool you. In fact, "It's usually done in full light of day," says Beverly Hills-based dermatologist Ava Shamban. In all seriousness, the treatment is a "combination of a microdermabrasion, followed by the application of PRP (platelet-rich plasma)," says Shamban. "The PRP is derived from the serum portion of the blood, which contains platelets. The platelets contain high levels of growth factors, which, when applied to the skin, will stimulate cell turnover."
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