“Selphyl is not a filler – it’s a truly regenerative treatment that involves harvesting the body’s own wound healing and regenerative growth factors to improve skin texture, as well as age-related changes like fine lines and laxity,” says Dr. Jennifer Pearlman, staff physician at Mount Sinai Hospital, menopause clinic and owner of PearlMD Rejuvenation, where the treatment is also offered.
Watch and wait: Growth factors contained in the plasma stimulate the release of the skin’s stem cells. The skin is being tricked into believing that it has been injured and must heal itself with new, fresh tissue. This somewhat sneaky process allows the skin to create new collagen, new blood vessels, and new cells. The results will not be immediate, so while you patiently wait a few weeks and even a few months, your skin will begin to transform itself.

So, what is it and how does it work, exactly? Don't let the name fool you. In fact, "It's usually done in full light of day," says Beverly Hills-based dermatologist Ava Shamban. In all seriousness, the treatment is a "combination of a microdermabrasion, followed by the application of PRP (platelet-rich plasma)," says Shamban. "The PRP is derived from the serum portion of the blood, which contains platelets. The platelets contain high levels of growth factors, which, when applied to the skin, will stimulate cell turnover."
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