Tell your doctor about all your medical conditions, including: plans to have surgery; had surgery on your face; have trouble raising your eyebrows; drooping eyelids; any other abnormal facial change; are pregnant or plan to become pregnant (it is not known if BOTOX® Cosmetic can harm your unborn baby); are breast-feeding or plan to (it is not known if BOTOX® Cosmetic passes into breast milk).
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Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.


Sclafani is enthusiastic about the injections for certain patients. "It's been terrific," he says. "It's not for everybody," he continues, saying that some patients don't see any difference from the treatment. For those for whom it works, it appears to last a long time. Sometimes patients come back in six to eight months to get further treatments done, Sclafani says.
First and foremost, Kim, as much as we love her (or hate to love her, or whatever), is dramatic AF. At no point during the treatment was I compelled to whimper and cry in pain. Sure, there were moments—most notably, when the Dermapen grazed over the area of my forehead just above my brows leading up to my hairline—where it felt like I was being scalped, but since it was so brief, my pain receptors didn’t even have the chance to trigger tears—or, more surprisingly, blood. 
Typically, the process includes the initial blood draw, then running the blood through a centrifuge to isolate the platelets. You'll then receive microneedling or microdermabrasion just before your PRPs are slathered across your face. This can be accompanied with or without radio frequency, too. "It sounds gory and mysterious, but in fact, it is central to our evolving understanding of the physiology of the skin and advanced techniques with which to improve the quality of the skin," says Shamban.
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