PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation. While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 As of March 2011 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation. Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications.
Watch and wait: Growth factors contained in the plasma stimulate the release of the skin’s stem cells. The skin is being tricked into believing that it has been injured and must heal itself with new, fresh tissue. This somewhat sneaky process allows the skin to create new collagen, new blood vessels, and new cells. The results will not be immediate, so while you patiently wait a few weeks and even a few months, your skin will begin to transform itself.
4) Isolating PRP: The drawn blood is placed in a centrifuge for 5 to 10 minutes. This equipment spins the blood at high speed to separate the lighter plasma from the rest of contents of the blood. This isolated platelet rich plasma is “activated” by a special process to begin releasing growth factors that, once injected into the body, will increase collagen production and have other healing effects.
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Platelets, Zeichner explains, are rich in growth factors, which essentially act as energy boots for our skin. This helps our skin function optimally, increasing everything from collagen to elastin, while also bringing antioxidant and hydrating properties. "Platelet-rich plasma is now commonly used topically as part of a regular facial, used along with microneedling to enhance penetration into the skin, and is even being injected into the skin in the same manner as dermal fillers," says Zeichner.