The Vampire FactLift™ procedure lasts about 30 minutes.  Blood is drawn from the patient’s arm.  The blood is placed in a centrifuge where it is processed to isolate the platelets from the red blood cells and other blood components.  The blood is then treated, most commonly with calcium chloride.  This process releases the PRFM (platelet rich fibrin matrix), growth-rich platelets.

"The term “vampire facial” may throw some people off, leading to a misconception that this is a quick, easy treatment," Hah said. "However, PRP therapy is a medical procedure that should always be performed by a physician who has specific experience with the technique. In addition to blood needing to be drawn safely and with sterile instruments, micro-injuries are created in the facial skin during the microneedling process—which can leave room for infection if the proper care is not taken."
Earlier this week, the New Mexico Department of Health announced the closure of a spa in Albuquerque after one of their clients reportedly developed an “unspecified infection” sometime after getting a “vampire facial.” During an inspection of the facility on Friday morning, health department officials became concerned about the way the spa was managing the storage, handling and disposal of needles.

When I expressed my concern for the blood-free end result, Dr. Peredo and Nurse Shellock explained that part of why Kim K looked so bloody is because, back in 2013 when that particular episode of Kim and Kourtney Take Miami aired, the normal vampire facial procedure was to apply whole blood to the skin while microneedling, where nowadays technology has advanced to using the most regenerating part of blood, the PRP. While both methods use blood drawn on site, the PRP method extracts the platelets from the red blood cells after being put through the centrifuge. And so, I finally understood why my Kim K-inspired expectations weren’t fully met. 
After using injectable fillers to achieve a more youthful appearance, your injector will draw your blood. Typically, we’ll only need to draw around 2 teaspoons. Your blood will be run through a centrifuge to separate and isolate platelet rich plasma, which is also known as growth factors. These specific “growth factors” have been identified to help heal damaged tissue. These growth factors have been known to work like magic to cause increased collagen and improved blood flow to the tissue.
One of the reasons the PRP Facial is so popular is because it works miracles on acne scars and stretch marks. It also increases skin’s elasticity, fights wrinkles by stimulating collagen, and has no side effects. How does it work? When Platelet-rich plasma is applied before and after microneedling it releases at least eight essential growth factors and signaling proteins into the skin. These work to repair tissue and blood vessels, promote the growth of new tissue, and boost healthy cell production.
The patient is numbed with a topical anesthetic gel.  The PRFM is then injected with a short, small gauge needle into the desired areas of the face.  The PRFM induces growth of new blood vessels, skin cells and collagen resulting in a healthy glow, better color, better tone, reduced wrinkles and sagging.  The new blood flow helps create volume and shape, lifting the skin and sculpting the face.  In 30 minutes, you are on your way to a new you with a more youthful appearance!
Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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