First, the physician (1)  isolates growth factors from the patient's blood.  Then (2), the provider uses a micro-needling device to create multiple micro-punctures --both driving the isolated growth factors into the skin & creating stimulus for tightening and rejuvenation of the collagen of the face. Then (3), these provider paints the growth factors onto the micro-punctures so that the growth factors soak into the tissue for further stimulation of tightening and skin rejuvenation.

The process starts with a careful assessment of your medical history and skin concerns. After determining you are a candidate for this treatment, blood is taken similar to a normal laboratory blood draw. This blood is then processed in our COLA certified moderately complex laboratory in a centrifuge that spins down your blood. We separate the blood components, filtering the portion of the blood which is called platelet-rich plasma or PRP. The PRP has a large amount of platelets (cells that help clot your blood when bleeding) and are very rich in growth factors and stem cells. After being activated the PRP is re-injected into the face in conjunction with a hyaluronic acid filler to simulate an injury that will help the body create new blood vessels and blood flow. It will also stimulate collagen production to help improve the texture of the skin.
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These platelets, when injected into certain areas of the face, can encourage blood flow, assist with the production of collagen, and activate multipotent stem cells already present in the skin. In time, this procedure will even stimulate the body to produce new skin cells, generating younger tissue and reducing the signs of aging throughout the treated area. This will promote healthy collagen production and restore vitality to the blood vessels and fatty tissues in the neck and face.


PRPs are one of the latest trends in beauty and skincare because of its ability to stimulate new cellular growth, purportedly improving skin tone and texture, smoothing fine lines and even promoting hair growth. Patients are advised to pop a pain pill or to apply numbing cream to diminish any pain from the initial blood draw, as well as the microneedling method.
PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation.[1] While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 As of March 2011 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation.[1] Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications.[1]
Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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