There's no evidence at all that this gory procedure works, and only the babiest starting evidence that injecting platelets into the skin works at all against the appearance of aging. But there probably is little harm, at least, to plasma injections because they deal with the patient's own body fluids, dermatologists say. The technologies dermatologists use for the facials are U.S. Food and Drug Administration approved for adding plasma to bone before orthopedic surgery... but not for wrinkle-busting.

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We may use numbing injections to make your procedure more comfortable. Dermal fillers often include some of this medication, called lidocaine, which is very similar to what dentists use when filling cavities. So we don’t always have to add more numbing injections, but it is available if needed. The numbing sensation lasts a few hours. When it wears off you shouldn’t expect to need any pain medication.
Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.

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When I expressed my concern for the blood-free end result, Dr. Peredo and Nurse Shellock explained that part of why Kim K looked so bloody is because, back in 2013 when that particular episode of Kim and Kourtney Take Miami aired, the normal vampire facial procedure was to apply whole blood to the skin while microneedling, where nowadays technology has advanced to using the most regenerating part of blood, the PRP. While both methods use blood drawn on site, the PRP method extracts the platelets from the red blood cells after being put through the centrifuge. And so, I finally understood why my Kim K-inspired expectations weren’t fully met. 

Platelets, Zeichner explains, are rich in growth factors, which essentially act as energy boots for our skin. This helps our skin function optimally, increasing everything from collagen to elastin, while also bringing antioxidant and hydrating properties. "Platelet-rich plasma is now commonly used topically as part of a regular facial, used along with microneedling to enhance penetration into the skin, and is even being injected into the skin in the same manner as dermal fillers," says Zeichner.
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