During a Vampire FaceLift®, the PRP is injected back into your face in a precise and defined manner. These injections can reduce fine lines and wrinkles and help brighten gaunt or ghoulish-looking skin. They may also help refresh and add volume to certain areas of the face, such as the under-eye hollows. In addition, many doctors are studying the use of PRP in wound healing.

Your doctor draws blood from your arm and spins it to separate out the plasma, which contains platelets. These are the proteins and growth factors that stimulate collagen production and thereby promote skin regeneration and rejuvenation. There are many kits available to isolate these growth factors, and platelet-rich plasma (PRP). Once collected, the platelet-rich plasma is injected back into your face.
This unique procedure uses the patient’s own blood so there is no risk or rejection or complications.  It is all natural unlike the injectable fillers that are on the market.  The procedure take only about 30 minutes in a safe and sterile environment.  Blood is drawn from the patient and then is put into a centrifuge where the growth-rich platelets are separated.  These platelets are then put into a calcium chloride solution which causes them to release growth factors.  The patient is numbed with a topical anesthetic and then the growth-factor platelets are injected into the areas needed.  There are no side effects, little or no discomfort and the patient is able to return to work.
Using numbing cream and a very small needle (for almost no pain), the patient’s own growth factors are injected back into her face in a particular way. These growth factors then activate multipotent stem cells already in the skin which is tricking them into “thinking” there’s been an injury and new younger tissue is generated. The multipotent stem cells then develop into new collagen, new blood vessels, and new fatty tissue trying to “repair” the skin that was never injured!
"The PRP is now highly concentrated with your body’s own natural growth factor proteins, with its regenerative and healing properties," Hah said. "Typically, it is applied to the face after a microneedling treatment has been performed, which creates small channels in the skin so the PRP can penetrate. The mirconeedling creates a stimulus that of turns on your body's natural healing systems. The concentrated growth factors then go to work to regenerate tissue and enhance natural healing processes."
The statement doesn't mention which specific practices might have led to infections. But hepatitis B, hepatitis C and HIV can all be spread through contact with bodily fluids, including blood. The owner of VIP Spa is also encouraging clients to get tested, though she told local news station KOB 4 that she always used new needles during the treatments.
But simply getting facial injections of dermal filler and PRP does not mean it's a Vampire Facelift. The true "Vampire Facelift" was designed and trademarked Dr. Charles Runels of Alabama. In order to use the vampire term in connection with a facial PRP injectable procedure, professionals must pay for Runels' special training, and use his specific techniques and HA fillers.
These platelets, when injected into certain areas of the face, can encourage blood flow, assist with the production of collagen, and activate multipotent stem cells already present in the skin. In time, this procedure will even stimulate the body to produce new skin cells, generating younger tissue and reducing the signs of aging throughout the treated area. This will promote healthy collagen production and restore vitality to the blood vessels and fatty tissues in the neck and face.
The Vampire Facelift® is actually not a surgical facelift at all, but rather a type of skin treatment using the body’s own natural healing and growth factors that are derived from your own blood (hence the name The Vampire Facelift®), combined with a hyaluronic acid dermal filler. The procedure is a near painless series of injections into strategic areas of the face to reduce wrinkles, add youthful volume, and improve the quality of your skin.

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That’s why it’s imperative that when you receive treatment (whether medical or for physical changes), you ensure that the needles used are either new or were properly sanitized. Before beginning a procedure, be sure to ask about their sanitizing procedures. Ask if you can watch them open a new needle or sanitize a used one. If they don’t use disposable needles, ask to watch the needle undergo its sanitization, and check that their sanitizer has been recently inspected. This may feel awkward at the time, but a true professional will understand your concern and the risks that are involved.
Before receiving KYBELLA®, tell your healthcare provider about all of your medical conditions, including if you: Have had or plan to have surgery on your face, neck, or chin; have had cosmetic treatments on your face, neck, or chin; have had or have medical conditions in or near the neck area; have had or have trouble swallowing; have bleeding problems; are pregnant or plan to become pregnant (it is not known if KYBELLA® will harm your unborn baby); are breastfeeding or plan to breastfeed (it is not known if KYBELLA® passes into your breast milk).

As far as risks go, there aren't as many as you might think. In fact, Shamban explained that the only risk you really run is bruising at the time of the venipuncture. Aside from the discomfort of a blood draw and bruising from injection or microneedling, Zeichner says the vampire facial is "extremely safe, as it is your body's own blood being recycled."
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