"While it has become incredibly popular and can yield wonderful results, it is not necessarily the miracle treatment some advertise it as," Hah said. "That being said, PRP has been used for last two decades to help treat musculoskeletal pain and regenerate cells; it is not a new “fad” treatment. In fact, studies have shown that PRP effectively promotes tissue remodeling in aging skin."
The most commonly reported side effects with JUVÉDERM® injectable gels included injection-site redness, swelling, pain, tenderness, firmness, lumps/bumps, bruising, discoloration, and itching. For JUVÉDERM VOLBELLA® XC, dryness was also reported. For JUVÉDERM VOLUMA® XC, most side effects were moderate and lasted 2 to 4 weeks. For JUVÉDERM® XC, JUVÉDERM VOLLURE™ XC, and JUVÉDERM® Ultra XC injectable gels, most side effects were mild or moderate and lasted 14 days or less. For JUVÉDERM VOLBELLA® XC, most side effects were mild or moderate and lasted 30 days or less.
Isolating PRP: The drawn blood is placed in a centrifuge for 5 to 10 minutes. This equipment spins the blood at high speed to separate the lighter plasma from the rest of contents of the blood. This isolated platelet rich plasma is “activated” with calcium chloride to begin releasing growth factors that, once injected into the body, will increase collagen production and have other healing effects.
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As far as risks go, there aren't as many as you might think. In fact, Shamban explained that the only risk you really run is bruising at the time of the venipuncture. Aside from the discomfort of a blood draw and bruising from injection or microneedling, Zeichner says the vampire facial is "extremely safe, as it is your body's own blood being recycled."