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There's no evidence at all that this gory procedure works, and only the babiest starting evidence that injecting platelets into the skin works at all against the appearance of aging. But there probably is little harm, at least, to plasma injections because they deal with the patient's own body fluids, dermatologists say. The technologies dermatologists use for the facials are U.S. Food and Drug Administration approved for adding plasma to bone before orthopedic surgery... but not for wrinkle-busting.
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Sclafani is enthusiastic about the injections for certain patients. "It's been terrific," he says. "It's not for everybody," he continues, saying that some patients don't see any difference from the treatment. For those for whom it works, it appears to last a long time. Sometimes patients come back in six to eight months to get further treatments done, Sclafani says.
The Vampire Facial, on the other hand, is a type of skin resurfacing treatment (such as microneedling or microdermabrasion) which is followed by microneedling of PRP into the skin. The benefit of this method of treatment is that the tiny needles used with microneedling “trick” your body into thinking there is an injury, so new collagen is produced. Though the tiny needles may make the skin look red or irritated for a short while after treatment, it is well known to look much worse than it feels! The results are extremely beneficial for those with fine lines or those who have acne scars or other imperfections they would like to improve.
"Platelet-rich plasma therapy, particularly when combined with other anti-aging treatments like microneedling, can help soften the appearance of common signs of aging, such as fine lines and loss of skin tone," he said. "Because it enhances your natural collagen production, it can also firm and smooth the skin for a more youthful complexion and reduce sun damage and scarring."
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These completely automatic and adjustable devices penetrate at the right speed and depth through the outer, superficial layer of the skin (the epidermis) into the slightly deeper layer (the dermis) just underneath. Nothing is injected; the procedure is really just the “needling” itself, which in turn stimulates the dermis to release certain special active biomolecules into the surrounding skin.
While your face will look red, swollen and bloody immediately after the treatment (it can last a few hours to up to three days after), the results (you’ll see glowing skin immediately but it can take a month or so for the full results, which last about three months, to surface) it provides for cellular rejuvenation are unparalleled because it shortens healing time and stimulates collagen. “Athletes have used it to heal sprains, and now dermatologists are using the technique for hair restoration,” says Dr. Cheung.

As far as risks go, there aren't as many as you might think. In fact, Shamban explained that the only risk you really run is bruising at the time of the venipuncture. Aside from the discomfort of a blood draw and bruising from injection or microneedling, Zeichner says the vampire facial is "extremely safe, as it is your body's own blood being recycled."
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