First, the injector (1) uses HA fillers to create a beautiful shape. (2) Then, the physician isolates growth factors from the patient’s blood.  (3) When these growth factors enter the face (injected by the physician), then muti-potent stem cells become activated to grow new tissue.  This new tissue includes new collagen, new fatty tissue (for smoothness), and new blood vessels (for a healthy glow).
PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation.[1] While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 As of March 2011 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation.[1] Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications.[1]
But, you know what wasn’t disappointing? The day-three results. While the hours immediately following the hour-long appointment were characterized by an unsightly red, ultra-puffy complexion (which was really just exacerbated by the fact that I have sensitive skin), with the help of an even layer of Alastin Regenerating Skin Nectar (the post-treatment product Dr. Peredo told me to use for the next week), by day two it looked like I had a low-key sunburn and day three my skin looked radiant and refreshed. 

You will be asked to drop smoking in advance of the operation. Certain medications that increase the risk of bleeding such as Aspirin, non-steroidal anti-inflammatory medications, and some vitamins/homeopathic regimens should be discontinued prior to surgery. Having long hair before the surgery is going to help you cover the incisions while they heal. Any chemical processing of your hair should be done prior to surgery.

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Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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