Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms including: loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.

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"Platelet-rich plasma therapy, particularly when combined with other anti-aging treatments like microneedling, can help soften the appearance of common signs of aging, such as fine lines and loss of skin tone," he said. "Because it enhances your natural collagen production, it can also firm and smooth the skin for a more youthful complexion and reduce sun damage and scarring."
The basic PRP treatment has been used for almost 20 years to accelerate the healing of wounds and burnt skin, and help athletes - including, reportedly, tennis ace Rafael Nadal - recover from injury. But it was when Dr Charles Runels from Alabama trademarked the name "Vampire Facelift" in 2010, during the craze for the Vampire Diaries and Twilight Saga, that the procedure became attractive for A-listers.
PRPs are one of the latest trends in beauty and skincare because of its ability to stimulate new cellular growth, purportedly improving skin tone and texture, smoothing fine lines and even promoting hair growth. Patients are advised to pop a pain pill or to apply numbing cream to diminish any pain from the initial blood draw, as well as the microneedling method.
Tell your doctor if you have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as Myobloc®, Dysport®, or Xeomin® in the past (tell your doctor exactly which product you received); have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine; take aspirin-like products or blood thinners.
"It’s rare for an incident like what happened in New Mexico to occur with PRP therapy, though it can be avoided by working with a qualified properly licensed physician provider," Hah said. "The spa operating in New Mexico did not have the credentials to perform this kind of medical procedure. Since their license expired, there was no oversight of the spa’s safety and cleanliness practices. Per the Department of Health’s findings, it appears the spa in question did not properly store, handle, or dispose of used needles."
During the procedure, you may experience sensations of pulling, tugging, mild pinching, intense cold, tingling, stinging, aching, and cramping at the treatment site. These sensations subside as the area becomes numb. Following the procedure, typical side effects include temporary redness, swelling, blanching, bruising, firmness, tingling, stinging, tenderness, cramping, aching, itching, or skin sensitivity, and sensation of fullness in the back of the throat after a submental area treatment. Rare side effects may also occur. The CoolSculpting® procedure is not for everyone. You should not have the CoolSculpting® procedure if you suffer from cryoglobulinemia, cold agglutinin disease, or paroxysmal cold hemoglobinuria. The CoolSculpting® procedure is not a treatment for obesity. Ask your doctor if CoolSculpting® is right for you. To learn more about what to expect, visit coolsculpting.com.

"The PRP is now highly concentrated with your body’s own natural growth factor proteins, with its regenerative and healing properties," Hah said. "Typically, it is applied to the face after a microneedling treatment has been performed, which creates small channels in the skin so the PRP can penetrate. The mirconeedling creates a stimulus that of turns on your body's natural healing systems. The concentrated growth factors then go to work to regenerate tissue and enhance natural healing processes."

Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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