The deal is this: Blood is drawn, usually from the client’s arm, then placed in a centrifuge in order to separate the plasma and the platelets from red blood cells. The resulting liquid is called platelet-rich plasma, or PRP. The plasma contains protein and other nutrients that are supposed to help stimulate skin cell growth and collagen. Then that material is either applied topically or injected into the face using microneedling techniques, which essentially involves puncturing the skin many times with super-tiny needles. The theory is that the holes help the growth factors and other nutrients get into deeper layers of the skin.
Because the procedure utilizes the body’s own rich blood, it revitalizes and enhances the skin in a way that synthetic products can’t without side effects or surgery.  The platelet growth factors, platelet rich fibrin matrix [PRFM], stimulate new growth and energy to correct lines, wrinkles and enhance color.  It uses your own body to help beautify your body.

Those who want to treat fine lines and slight sagging on the lower part of the face (like the chin) and to treat laxity in the décolleté area, as well as cleavage crepiness. It can also be used to treat acne scars and divots, cellulite, and even hair loss. Crow’s feet around the eye area can also be treated. “Selphyl is unique and distinct  – it’s the patient’s own regenerative potential in their blood re-injected back into the skin,” says Dr. Pearlman. “People who seek this [procedure] don’t want anything foreign injected [into their face] at all.” If you have any type of bleeding disorder or clotting problem, or if your platelets are low (thrombocytopenia), you may not be a candidate for this treatment.


So, what is it and how does it work, exactly? Don't let the name fool you. In fact, "It's usually done in full light of day," says Beverly Hills-based dermatologist Ava Shamban. In all seriousness, the treatment is a "combination of a microdermabrasion, followed by the application of PRP (platelet-rich plasma)," says Shamban. "The PRP is derived from the serum portion of the blood, which contains platelets. The platelets contain high levels of growth factors, which, when applied to the skin, will stimulate cell turnover."
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