Vampires are known for their red eyes, alabaster complexion and sharp fangs. Vampire injections don't promise any of these outcomes. Instead, they reduce fine lines and wrinkles, restore volume and get rid of that gaunt, anemic look. Facial plastic surgeons who perform this procedure often overfill the area by 20 percent, because much of the PRP will be reabsorbed by your body. In general, the procedure takes about 30 minutes from start to finish.
If the procedure is carried out properly, the risks are low, except for people with blood-related medical issues, especially those which require blood-thinning medication. The microneedling causes temporary bleeding—hence the name "Vampire facial". Meanwhile, bruising, swelling, redness and pain may persist over the injection site, but these side effects usually disappear within a few days.
“Selphyl is not a filler – it’s a truly regenerative treatment that involves harvesting the body’s own wound healing and regenerative growth factors to improve skin texture, as well as age-related changes like fine lines and laxity,” says Dr. Jennifer Pearlman, staff physician at Mount Sinai Hospital, menopause clinic and owner of PearlMD Rejuvenation, where the treatment is also offered.
This injection of PRP into the face activates multipotent stem cells and tricks the body into generating new tissue, as it would after an injury. The patient’s system will naturally grow collagen for moisture and a more youthful face, new fatty tissue for smoothness and new blood vessels for a glowing complexion. The procedure was inspired by how your body heals after an injury.

Sclafani's injections are an off-label use of Selphyl, the Aesthetic Factors technology that separates plasma from the blood. Bruce Katz, another New York dermatologist who offers individual injections, uses a similar technology made by the Swiss company Regen Lab. Katz advertises "twilight plasma renewal treatment" on his website. His patients get about 20 injections at once in the face, neck and décolleté, he says.
A. Using blood plasma to heal and regenerate the body originated from Orthopedics (FDA approved) and has numerous studies substantiating the regeneration and healing of injuries and tissue repair. PRP evolved from there for the purpose of skin rejuvenation. PRP means PLATELET RICH PLASMA, where the platelet concentration is generally considered to be double the normal concentration in whole blood. Red blood cells (RBC) and white blood cells (WBC) should be removed as much as possible from a PRP preparation. Some kits that tout high platelet concentrations often do so at the expense of having contaminating RBCs or WBCs – these cells are known to have inflammatory and catabolic effects – just the opposite of the desired effect. If the PRP in the syringe has any tinge of pink or red, it is mostly likely that you are injecting a preparation that has RBC contamination. The ideal PRP solution will be a golden, straw-like color.
The key ingredient for the Vampire Facelift® is the platelet-rich fibrin matrix, which is derived from the patient’s own blood before being mixed with other factors. These properties make platelet-rich fibrin matrix an ideal natural serum for rejuvenating facial skin quality, as it increases collagen production, increases blood supply, and triggers new skin and fatty tissue generation, thus creating the youthful appearance that comes with generating new, healthier skin in a safe and natural way.
Isolating PRP: The drawn blood is placed in a centrifuge for 5 to 10 minutes. This equipment spins the blood at high speed to separate the lighter plasma from the rest of contents of the blood. This isolated platelet rich plasma is “activated” with calcium chloride to begin releasing growth factors that, once injected into the body, will increase collagen production and have other healing effects.
Isolating PRP: The drawn blood is placed in a centrifuge for 5 to 10 minutes. This equipment spins the blood at high speed to separate the lighter plasma from the rest of contents of the blood. This isolated platelet rich plasma is “activated” with calcium chloride to begin releasing growth factors that, once injected into the body, will increase collagen production and have other healing effects.

The facial, which is technically a Platelet-Rich Plasma (PRP) treatment, is, according to some skin care experts one of the best anti-aging procedures out there. “PRP is created from your own blood. It involves a simple blood draw into a special test tube, which is then spun in a centrifuge so that the plasma, with millions of platelets, floats to the top,” says Willowbrook, IL, dermatologist Jessie Cheung, MD. The PRP solution is then used in tandem with micro needling, creating hundreds of microscopic holes in the skin (the solution is applied to the skin after the holes have been made).
But, you know what wasn’t disappointing? The day-three results. While the hours immediately following the hour-long appointment were characterized by an unsightly red, ultra-puffy complexion (which was really just exacerbated by the fact that I have sensitive skin), with the help of an even layer of Alastin Regenerating Skin Nectar (the post-treatment product Dr. Peredo told me to use for the next week), by day two it looked like I had a low-key sunburn and day three my skin looked radiant and refreshed. 
Most likely, says Shamban. Those with "premature wrinkles, high levels of solar damage, or anyone who wants an even tone and fresher appearance to their skin," is an ideal candidate for the procedure, she says. However, Zeichner warns that if you have a history of blood diseases, including clotting or bleeding disorders, you should not seek PRP treatment.
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