A. Think of Selphyl® PRFM as the next generation PRP. The Selphyl® System is designed for the safe and rapid preparation of Platelet-rich Fibrin Matrix (PRFM) from a small sample of blood (only 10cc). Many PRP systems require operator skill, have varying results and have extensive contamination with red blood cells and white blood cells. Selphyl® removes virtually all contaminating cells and is independent of operator technique. PRP is converted to PRFM through a controlled process (mixed w/ calcium chloride in a vial) to form a fibrin matrix scaffold that serves to protect and preserve platelets, thus creating more therapeutic rejuvenation.
When I’m conducting my aesthetic PRP training in Beverly Hills & Nashville for doctors and clinic staff on how to perform PRP aesthetic procedures in the office or discussing the procedures with patients, one of the most frequent questions I hear is: “What’s the difference between the Vampire Facelift and the Vampire Facial?” They certainly sound similar, so the confusion isn’t surprising. Even though both of these trademarked procedures utilize PRP (platelet rich plasma), there is actually a significant difference in how they are completed and the results they provide.
A Stem Cell Facelift with Fat Transfer combines PRP with Nanofat and Fat Transfer. For those with thin, sagging skin and loss of fat volume, this offers the longest-lasting and most natural results possible. Nanofat is a process of harvesting the stem cells in your fat. In this procedure, we combine those stem cells with the growth and healing factors of PRP for skin texture, tone, and elasticity. We also use your own fat, taken from your midsection, to replace what your face has lost with age (or weight loss). This procedure creates brand new cells, for results that are all you. It is more expensive than a Vampire Facelift and does have about 3-7 days of downtime.
Most SkinMedica® products are intended to meet the FDA’s definition of a cosmetic product, an article applied to the human body to cleanse, beautify, promote attractiveness, and alter appearances. These SkinMedica® products are not intended to be drug products that diagnose, treat, cure, or prevent any disease or condition. These products have not been approved by the FDA, and the statements have not been evaluated by the FDA.
A. These names are referring to the use of platelets or “liquid gold” taken from your blood, to rejuvenate skin by methods of fractionating it into the skin or injecting it into the skin. At FACE we prefer to do an overall therapeutic dose of PRP/ PRFM which can increase the thickness of your skin by 10-12% all over, then go in and use fillers to target specific areas that have more substantiated volume loss.
PRFM has been available on the U.S. market since 2009. It was developed and is marketed by the Aesthetic Factors corporation.[1] While a platelet extraction centrifuge was cleared by the U.S. Food and Drug Administration (FDA) in 2002 As of March 2011 platelets extracted in this centrifuge have not been cleared or approved by the FDA for facial rejuvenation.[1] Nonetheless, Selphyl has been described as a "FDA approved dermal filler" in YouTube videos and trade publications.[1]
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The effects of the procedure improve for 2 to 3 months after the procedure and last for at least 1 to 2 years! Unlike most procedures, the Vampire Facelift (R) offers a way of restoring shape, and improving tone and texture, as well as literally rejuvenating new and younger tissue! The multipotent stem cells then develop into new collagen, new blood vessels, and new fatty tissue trying to “repair” the skin that was never injured! The result…younger-appearing skin!

So, what is it and how does it work, exactly? Don't let the name fool you. In fact, "It's usually done in full light of day," says Beverly Hills-based dermatologist Ava Shamban. In all seriousness, the treatment is a "combination of a microdermabrasion, followed by the application of PRP (platelet-rich plasma)," says Shamban. "The PRP is derived from the serum portion of the blood, which contains platelets. The platelets contain high levels of growth factors, which, when applied to the skin, will stimulate cell turnover."
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