These completely automatic and adjustable devices penetrate at the right speed and depth through the outer, superficial layer of the skin (the epidermis) into the slightly deeper layer (the dermis) just underneath. Nothing is injected; the procedure is really just the “needling” itself, which in turn stimulates the dermis to release certain special active biomolecules into the surrounding skin.
The Vampire Facial requires little recovery time. There may be redness and some tenderness on the first day that appears much like sunburn. Occasionally some bruising may occur. The initial redness will subside on the second day, and some patients then notice some swelling and a sandpaper texture to the skin the day after treatment. By the third day, the swelling should diminish. The sandpaper texture to the skin may persist for up to a week.
“Selphyl is not a filler – it’s a truly regenerative treatment that involves harvesting the body’s own wound healing and regenerative growth factors to improve skin texture, as well as age-related changes like fine lines and laxity,” says Dr. Jennifer Pearlman, staff physician at Mount Sinai Hospital, menopause clinic and owner of PearlMD Rejuvenation, where the treatment is also offered.
First, the injector (1) uses HA fillers to create a beautiful shape. (2) Then, the physician isolates growth factors from the patients blood.  (3) When these growth factors enter the face (injected by the physician), then multi-potent stem cells become activated to grow new tissue.  This new tissue includes new collagen, new fatty tissue (for smoothness), and new blood vessels (for a healthy glow).

In laymen's terms: It's a facial that essentially uses, "your own blood to help promote the healthy activity of your skin cells," says Joshua Zeichner, the director of cosmetic and clinical research in dermatology at Mount Sinai Hospital in New York City. Our blood is comprised of red blood cells and serum, which contain our white blood cells and platelets.
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